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HbA1c (by HPLC) 糖化血色素

H047G

Specimen Required

3 mL EDTA-wb

Schedule

Monday-Saturday

Specimen Stability

Ambient:

72 hr

Refrigerated:

7 days

Frozen:

Reference Interval

Reference intervals (NGSP):
Non-diabetic range (>18 years)	4.0 - 6.0 %
- Increased risk for future diabetes	5.7 - 6.4 %
- Diagnosing diabetes (at least 2 occasions)	≧ 6.5 %
Diabetic adults >19 years old:
- Goal of therapy	< 7.0 %
- Action suggested	> 8.0 %
Average blood glucose level (eAG) correlated with HbA1c
A1c	eAG in past 8-12 weeks
5 %	97 mg/dL or 5.4 mmol/L
6 %	126 mg/dL or 7.0 mmol/L
7 %	154 mg/dL or 8.6 mmol/L
8 %	183 mg/dL or 10.2 mmol/L
9 %	212 mg/dL or 11.8 mmol/L
10 %	240 mg/dL or 13.4 mmol/L
11 %	269 mg/dL or 14.9 mmol/L
12 %	298 mg/dL or 16.5 mmol/L

Reference Notes and Guidelines

1. eAG levels reflect the average glucose concentration over the past 8-12 weeks, and provides a more useful indication of long-term glycemic control than blood and urinary glucose determination. Formula: eAG (mg/dL) = 28.7 x HbA1c - 46.7

2. This HbA1c test is traceable to the Diabetes Control and Complications Trial (DCCT) reference study and is certified by the NGSP.

3. Interferences in HBA1c test may include:

- High Hb F (>30%)

- High Hb H (H Disease)

- High Hb Bart's Disease

- Homozygous Hb SS, Hb CC (no Hb-A present)

- Double heterozygous Hb SC (no Hb-A present)

- Other Hb variants

- Other severe anemia

For samples with interference suggest perform other tests such as Fructosamine or, if clinically indicated, a Hb Pattern for the presence of variants.

Source:

1. American Diabetes Association: Standards of medical care for patients with diabetes mellitus. Diabetes Care 2010;33:S11-S61.

2. Nathan DM, Kuenen J, Borg R, et al: Translating the A1c assay into estimated average glucose values. Diabetes Care 2008 Aug;31:1473-1478

Components

Name

Reference Interval

HbA1c 糖化血色素

Reference intervals (NGSP):
Non-diabetic range (>18 years)	4.0 - 6.0 %
- Increased risk for future diabetes	5.7 - 6.4 %
- Diagnosing diabetes (at least 2 occasions)	≧ 6.5 %
Diabetic adults >19 years old:
- Goal of therapy	< 7.0 %
- Action suggested	> 8.0 %
Average blood glucose level (eAG) correlated with HbA1c
A1c	eAG in past 8-12 weeks
5 %	97 mg/dL or 5.4 mmol/L
6 %	126 mg/dL or 7.0 mmol/L
7 %	154 mg/dL or 8.6 mmol/L
8 %	183 mg/dL or 10.2 mmol/L
9 %	212 mg/dL or 11.8 mmol/L
10 %	240 mg/dL or 13.4 mmol/L
11 %	269 mg/dL or 14.9 mmol/L
12 %	298 mg/dL or 16.5 mmol/L

8/28/2025 3:09:25 AM