| 1. The test result should be used in conjunction with clinical evaluation and other diagnostic procedures. |
| 2. If an acute infection is suspected, suggest a second sample 14-21 days later and test for both IgG and IgM antibodies to look for seroconversion or a singificant rise in antibody level. |
| 3. Results in IgG detection in neonates must be interpreted with caution, since maternal IgG is transferred passively from the mother to the foetus before birth. IgM assays are generally more useful indicators of infection in children below 6 months of age. |
| 4. Enzyme immunoassay tests to detect viral antibodies has several limitations. Therefore, if clinically indicated, confirmation by other methodologies or other tests are recommended. |
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| Source: Vircell Measles VirClia IgG Monotest package insert. 07/2015. |