HbA1c (by HPLC) 糖化血色素	H047
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Specimen Required 3 mL EDTA-wb	Schedule Monday-Saturday
Specimen Stability Ambient: 72 hr Refrigerated: 7 days Frozen:
Reference Interval Reference intervals (NGSP): Non-diabetic range (>18 years) 4.0 - 6.0 % - Increased risk for future diabetes 5.7 - 6.4 % - Diagnosing diabetes (at least 2 occasions) ≧ 6.5 % Diabetic adults >19 years old: - Goal of therapy < 7.0 % - Action suggested > 8.0 % Average blood glucose level (eAG) correlated with HbA1c A1c eAG in past 8-12 weeks 5 % 97 mg/dL or 5.4 mmol/L 6 % 126 mg/dL or 7.0 mmol/L 7 % 154 mg/dL or 8.6 mmol/L 8 % 183 mg/dL or 10.2 mmol/L 9 % 212 mg/dL or 11.8 mmol/L 10 % 240 mg/dL or 13.4 mmol/L 11 % 269 mg/dL or 14.9 mmol/L 12 % 298 mg/dL or 16.5 mmol/L
Reference Notes and Guidelines Click here for more details. Reference Notes and Guidelines 1. eAG levels reflect the average glucose concentration over the past 8-12 weeks, and provides a more useful indication of long-term glycemic control than blood and urinary glucose determination. Formula: eAG (mg/dL) = 28.7 x HbA1c - 46.7 2. This HbA1c test is traceable to the Diabetes Control and Complications Trial (DCCT) reference study and is certified by the NGSP. 3. Interferences in HBA1c test may include: - High Hb F (>30%) - High Hb H (H Disease) - High Hb Bart's Disease - Homozygous Hb SS, Hb CC (no Hb-A present) - Double heterozygous Hb SC (no Hb-A present) - Other Hb variants - Other severe anemia For samples with interference suggest perform other tests such as Fructosamine or, if clinically indicated, a Hb Pattern for the presence of variants. Source: 1. American Diabetes Association: Standards of medical care for patients with diabetes mellitus. Diabetes Care 2010;33:S11-S61. 2. Nathan DM, Kuenen J, Borg R, et al: Translating the A1c assay into estimated average glucose values. Diabetes Care 2008 Aug;31:1473-1478

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