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Estradiol (E2) (by ECL) 雌二醇

R016

Specimen Required

3 mL Pl (1 mL serum)

Schedule

Monday-Saturday

Notes

Updated note on 12 Aug 2022

Specimen Stability

Ambient:

24 hr

Refrigerated:

8 days

Frozen:

1 month

Reference Interval: Conv. Units

Females, adult
Follicular phase	12 - 233 pg/mL
Ovulation phase	41 - 398 pg/mL
Luteal phase	22 - 341 pg/mL
Postmenopausal	<5 (Median)
Pregnancy
1st trimester	154 - 3243 pg/mL
2nd trimester	1561 - 21280 pg/mL
3rd trimester	8525 - >30000 pg/mL
Males, adult	26 - 61 pg/mL

Reference Interval: S.I. Units

Females, adult
Follicular phase	45 - 854 pmol/L
Ovulation phase	151 - 1461 pmol/L
Luteal phase	82 - 1251 pmol/L
Postmenopausal	<18 (Median)
Pregnancy
1st trimester	563 - 11902 pmol/L
2nd trimester	5729 - 78098 pmol/L
3rd trimester	31287 - >110100 pmol/L
Males, adult	95 - 223 pmol/L

Reference Notes and Guidelines

1. Falsely increased results may be seen in patients on high doses of biotin (i.e. > 5mg/day). Samples should only be collected from these patients at least 8 hours following the last biotin administration so as to avoid potential interference.

2. The analytical sensitivity of the Estradiol assay is 5 pg/mL and the functional sensitivity is 25 pg/mL. The functional sensitivity is defined at the lowest concentration that can be measured with a CV of ≦ 20%. Therefore, for valuse lower than 25 pg/mL, the reproducibility may be poor. Please review low results together with clinical findings.

Source: Roche cobas Estradiol III package insert: ref 06656021 (2022-04), V7.0

8/28/2025 3:08:15 AM